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生命最初五年的血压:与种族群体(黑人或白人)及父母高血压的关系。

Blood pressure during the first five years of life: relation to ethnic group (black or white) and to parental hypertension.

作者信息

Schachter J, Kuller L H, Perfetti C

出版信息

Am J Epidemiol. 1984 Apr;119(4):541-53. doi: 10.1093/oxfordjournals.aje.a113771.

Abstract

Blood pressure was measured in 392 healthy, full-term, appropriate-weight infants and was measured again at 6, 15, 24, 36, 48, and 60 months of age. Systolic pressure rose from birth to six months of age, remained at a plateau until 15 months of age, and from 24 to 60 months rose an average of 1 mmHg per year. Diastolic pressure rose from birth to 24 months but showed little change from 24 to 60 months. The correlation of systolic with diastolic pressure decreased seriatim from birth to 60 months. Blood pressure did not vary as a function of ethnic group, sex, or socioeconomic status during the first five years of life. The association of body size with blood pressure was no more than modest during this period, but seemed to be closer for females than for males. A closer child-parent association was found for heart rate than for blood pressure. The child's heart rate was inversely associated with the parent's blood pressure although the child's blood pressure was not associated with the parent's pressure. During the first five years of life, a low heart rate may be a more significant risk factor for adult hypertension than elevated blood pressure.

摘要

对392名健康、足月、体重适宜的婴儿进行了血压测量,并在其6、15、24、36、48和60月龄时再次测量。收缩压从出生到6个月龄上升,在15个月龄前保持平稳,从24到60个月龄平均每年上升1 mmHg。舒张压从出生到24个月龄上升,但从24到60个月龄变化不大。从出生到60个月龄,收缩压与舒张压的相关性依次降低。在生命的前五年中,血压不会因种族、性别或社会经济地位而有所不同。在此期间,体型与血压的关联程度不高,但女性的关联似乎比男性更紧密。发现心率的亲子关联比血压更紧密。尽管孩子的血压与父母的血压没有关联,但孩子的心率与父母的血压呈负相关。在生命的前五年中,低心率可能比血压升高更易成为成人高血压的重要风险因素。

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