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生命最初五年的心率:与种族群体(黑人或白人)及父母高血压的关系。

Heart rate during the first five years of life: relation to ethnic group (black or white) and to parental hypertension.

作者信息

Schachter J, Kuller L H, Perfetti C

出版信息

Am J Epidemiol. 1984 Apr;119(4):554-63. doi: 10.1093/oxfordjournals.aje.a113772.

Abstract

Heart rate was measured in 392 healthy, full-term, appropriate-weight infants and was measured again at 6, 15, 24, 36, 48, and 60 months of age. Heart rate increased from newborn to six months of age and then decreased seriatim. Heart rate did not vary as a function of socioeconomic status or of sex. Blacks had higher heart rates than whites as newborns and at six months of age; at the older ages the difference was no longer significant. The slowing of heart rate with age was greater among blacks. Heart rate was inversely associated with weight and with height, but showed no association with blood pressure. A significant child-mother correlation of heart rate was found at two ages. No significant child-mother correlations of systolic or of diastolic blood pressure were found. Thus, a closer child-parent association was found for heart rate than for blood pressure. Offspring of a parent with a history of hypertension had slower heart rates than offspring neither of whose parents had a history of hypertension. Neither the child's systolic nor diastolic blood pressure varied with the presence or absence of a parental history of hypertension. Results suggest that during the first five years of life a child's slower heart rate may be a better index of risk of adult hypertension than a child's elevated blood pressure.

摘要

对392名健康、足月、体重正常的婴儿进行了心率测量,并在其6、15、24、36、48和60月龄时再次测量。心率从新生儿期到6个月龄增加,然后依次下降。心率不因社会经济地位或性别而变化。黑人新生儿和6个月龄时的心率高于白人;在较大年龄时,这种差异不再显著。黑人中随年龄增长心率减慢的幅度更大。心率与体重和身高呈负相关,但与血压无关。在两个年龄段发现儿童与母亲的心率存在显著相关性。未发现儿童与母亲的收缩压或舒张压存在显著相关性。因此,发现心率方面儿童与父母的关联比血压方面更紧密。父母有高血压病史的后代心率比父母均无高血压病史的后代慢。儿童的收缩压和舒张压均不因父母有无高血压病史而变化。结果表明,在生命的头五年中,儿童心率较慢可能比儿童血压升高更能作为成人高血压风险的指标。

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