Lewis R V, Micanovic R, Ray P, Blacher R, Stern A
Arch Biochem Biophys. 1984 Apr;230(1):154-7. doi: 10.1016/0003-9861(84)90096-1.
An octapeptide and decapeptide which are not derived from proenkephalin were isolated from ovine adrenal chromaffin granules. Their sequences are Asn-Leu-Asp -Pro-Lys-Leu-Asp-Leu and Val-Ala-Glu-Leu-Asp-Gln-Leu-Leu-His-Tyr. These two peptides were found to be derived from a single precursor peptide which has also been isolated and sequenced. The proteolytic cleavage occurs at a Lys-Arg site typical of prohormone to hormone cleavages.
