Alvarez Chiva V, Mato J M
Biochem J. 1984 Mar 1;218(2):637-9. doi: 10.1042/bj2180637.
Rat liver cytosol contains a heat-stable factor which inhibits phospholipid methylation by rat liver microsomes. The effect of this factor on lipid methylation was dose- and pH-dependent. This factor has an Mr of approx. 3200 as estimated by gel filtration. It could not be extracted by chloroform/methanol (2:1, v/v), and its action was inhibited by incubation with subtilisin.
大鼠肝脏胞质溶胶含有一种热稳定因子，该因子可抑制大鼠肝脏微粒体的磷脂甲基化。此因子对脂质甲基化的作用呈剂量和pH依赖性。通过凝胶过滤估计，该因子的相对分子质量约为3200。它不能被氯仿/甲醇（2:1，v/v）提取，并且与枯草杆菌蛋白酶一起孵育可抑制其活性。
