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蓝光光疗对人淋巴细胞染色体的影响

[Effects of phototherapy with blue light on chromosomes from human lymphocytes].

作者信息

Ghiazza G, Zavarise G, Ferraro G, Barbero A, Grillo G

出版信息

Boll Soc Ital Biol Sper. 1984 Mar 30;60(3):673-8.

PMID:6712837
Abstract

The dangerous effects of phototherapy have been matter of discussion in recent years. In order to evaluate its in vitro action on the human DNA, the authors have performed the karyotypic analysis on 20 cultures of lymphocytes. In different times 16 cultures have been exposed to the action of a "blue light" fluorescent lamp, commonly used for the treatment of neonatal jaundice. The authors have not evidenced any morphological or numerical change of the karyotype in any of the cultures.

摘要

近年来,光疗的危险作用一直是讨论的话题。为了评估其对人类DNA的体外作用,作者对20份淋巴细胞培养物进行了核型分析。在不同时间,16份培养物暴露于常用于治疗新生儿黄疸的“蓝光”荧光灯下。作者未发现任何一份培养物的核型有任何形态或数量上的变化。

相似文献

1
[Effects of phototherapy with blue light on chromosomes from human lymphocytes].蓝光光疗对人淋巴细胞染色体的影响
Boll Soc Ital Biol Sper. 1984 Mar 30;60(3):673-8.
2
[Cytogenetic studies of human lymphocytes following blue light irradiation in vitro].[体外蓝光照射后人淋巴细胞的细胞遗传学研究]
Acta Biol Med Ger. 1980;39(2-3):229-36.
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Phototherapy increases DNA damage in lymphocytes of hyperbilirubinemic neonates.光疗会增加高胆红素血症新生儿淋巴细胞中的DNA损伤。
Mutat Res. 2008 Jun 30;654(1):93-5. doi: 10.1016/j.mrgentox.2007.06.013. Epub 2008 Apr 18.
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Enhancement by bilirubin of DNA damage induced in human cells exposed to phototherapy light.胆红素对接受光疗照射的人体细胞中DNA损伤的增强作用。
Pediatr Res. 1984 Jan;18(1):3-6.
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Double direction phototherapy and light-induced genetic abnormalities in human lymphocytes.双向光疗与人类淋巴细胞中的光诱导基因异常
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Analysis of chromosome aberrations after exposure to ionizing radiation in "in vitro" cultures of human lymphocytes by means of BrdU incorporation.通过溴脱氧尿苷掺入法对人淋巴细胞“体外”培养物中电离辐射暴露后的染色体畸变进行分析。
Boll Soc Ital Biol Sper. 1980 Apr 15;56(7):719-24.
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Randomized controlled trial of compact fluorescent lamp versus standard phototherapy for the treatment of neonatal hyperbilirubinemia.紧凑型荧光灯与标准光疗治疗新生儿高胆红素血症的随机对照试验。
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[Mutagenicity of blue light. I. Effect of the time of irradiation, irradiation mode and cell density on the rate of chromosome mutations in lymphocyte cultures].[蓝光的致突变性。I. 照射时间、照射方式和细胞密度对淋巴细胞培养物中染色体突变率的影响]
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[Mutagenicity of blue light. II. Effect of the culture medium and bilirubin on the rate of chromosome mutations in lymphocyte cultures].蓝光的致突变性。II. 培养基和胆红素对淋巴细胞培养物中染色体突变率的影响
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