Schroeter C
Acta Biol Med Ger. 1980;39(2-3):229-36.
Human lymphocyte cultures were exposed for 0, 2, 4, 6, 8, 10, 12, and 14 h to the rays of the bluelight lamp NC-4400-04 developed by VEB Narva (Berlin) for the phototherapy of icterus neonatorum. The experiments revealed (1) a significant difference in the chromosomal aberration rate between bluelight treated and non-treated cultures and (2) a dependence of the aberration rate on the length of exposure. After the same duration of exposure the individual test series showed a great variation of aberration frequency. Chromatid gaps and breaks, chromosome gaps and breaks, chromatid translocations, and dicentric chromosomes were found to be induced. The majority of aberrations comprised gaps and breaks on the chromatid level.
将人类淋巴细胞培养物分别暴露于由德国国营柏林纳瓦公司（VEB Narva，Berlin）研制的用于新生儿黄疸光疗的NC - 4400 - 04蓝光灯下0、2、4、6、8、10、12和14小时。实验结果显示：（1）蓝光处理组与未处理组培养物的染色体畸变率存在显著差异；（2）畸变率与暴露时长有关。在相同暴露时长后，各个测试系列的畸变频率差异很大。发现诱导产生了染色单体间隙和断裂、染色体间隙和断裂、染色单体易位以及双着丝粒染色体。大多数畸变表现为染色单体水平的间隙和断裂。
