Döhler J R, Hamelmann H, Lasson U
Chirurg. 1984 Mar;55(3):174-8.
Benign by nature, aggressive fibromatoses (desmoid fibromas) may represent as difficult therapeutic problems as malignant tumours. When subtotally resected they tend to recur. But spontaneous regression is possible. Expense and limits of their surgical treatment are discussed with reference to seven patients. In five cases primary affliction of bone was evident. There are three reports given in detail: In the first, malignant transformation may be due to radiation therapy and hemipelvectomy could not prevent recurrence. In the second, spontaneous regression of untreated pelvic affection may have occurred. In the third, several resections and amputation of the leg failed to cure congenital infantile fibromatosis.
侵袭性纤维瘤病(韧带样纤维瘤)本质上是良性的,但可能像恶性肿瘤一样带来棘手的治疗难题。次全切除后易复发,但也有可能自然消退。结合7例患者探讨了其手术治疗的费用及局限性。5例有明显的原发性骨受累。详细给出了3例报告:第一例中,恶性转化可能归因于放射治疗,半骨盆切除术未能阻止复发;第二例中,未经治疗的盆腔病变可能出现了自然消退;第三例中,多次腿部切除和截肢未能治愈先天性婴儿纤维瘤病。