Reffo G C, Turrin M, Gabellini A, Forattini C
Eur J Clin Pharmacol. 1984;26(1):19-22. doi: 10.1007/BF00546702.
Ten patients suffering from refractory congestive heart failure were treated orally with Ibopamine 100 mg. The haemodynamic effects were evaluated with a Swan-Ganz catheter and thermodilution technique, 1 and 2 h after treatment. Ibopamine significantly increased the cardiac index and stroke work index, and decreased pulmonary pressure and the pulmonary and peripheral vascular resistances without affecting heart rate or blood pressure.
10例难治性充血性心力衰竭患者口服100毫克异波帕明进行治疗。采用Swan-Ganz导管和热稀释技术在治疗后1小时和2小时评估血流动力学效应。异波帕明显着增加心脏指数和每搏作功指数,并降低肺动脉压、肺血管阻力和外周血管阻力,而不影响心率或血压。