Schneck H J, von Hundelshausen B, Tempel G, Oberdorfer A, Rastetter J
Fortschr Med. 1984 Mar 15;102(10):263-8.
Blood levels of the immunoglobulins A, G and M were determined in a group of thirty patients, who had been splenectomized subsequent to splenal trauma, as part of a series of follow-up studies on polytrauma patients. These levels were compared with the corresponding values of an otherwise similar group of patients who had not been splenectomized. With few exceptions the majority of globulin levels in both groups were with the norm. The levels of IgG and IgA were significantly higher in the group of splenectomized patients, the IgM level was significantly lower than that of the comparison group of non-splenectomized patients. The medical history of the splenectomized patients showed no increase in susceptibility to infections and the average globulin levels were also well within the norm. Therefore, the clinical significance of these findings seems doubtful.
作为对多发伤患者一系列随访研究的一部分，对30例因脾外伤后行脾切除术的患者测定了免疫球蛋白A、G和M的血药浓度。将这些水平与另一组未行脾切除术但其他情况相似的患者的相应值进行比较。除少数例外，两组的大多数球蛋白水平均在正常范围内。脾切除患者组的IgG和IgA水平显著高于未行脾切除的对照组，IgM水平显著低于未行脾切除的对照组。脾切除患者的病史显示其对感染的易感性没有增加，平均球蛋白水平也在正常范围内。因此，这些发现的临床意义似乎值得怀疑。
