Ward C A, Koheil A, Johnson W R, Madras P N
J Biomed Mater Res. 1984 Mar;18(3):255-69. doi: 10.1002/jbm.820180303.
The activation of the rabbit complement system by each of three different synthetic materials is reported. Samples of each type of material were subjected to one of two different priming procedures. One priming procedure was intended to remove the air nuclei from the surface roughness of the materials; the other procedure was just the normal one. It was found that the removal of the air nuclei during priming reduced the complement activation by each of the two materials of lower surface tension, but not by a statistically significant amount for the material of highest surface tension, cellophane. For the denucleated samples of the three materials, the amount of complement activation was found to correlate with the critical surface tension of the materials; if the samples of the materials were normally primed, there was no correlation of the amount of complement activation with the critical surface tension of the material.
据报道，三种不同的合成材料均可激活兔补体系统。每种材料的样本都进行了两种不同的预处理程序之一。一种预处理程序旨在去除材料表面粗糙度中的气核；另一种程序则是常规程序。结果发现，预处理过程中去除气核可降低两种表面张力较低的材料的补体激活，但对于表面张力最高的材料玻璃纸而言，降低幅度无统计学意义。对于三种材料的去核样本，发现补体激活量与材料的临界表面张力相关；如果材料样本进行常规预处理，则补体激活量与材料的临界表面张力无关。
