Shafik A
J Clin Gastroenterol. 1984 Apr;6(2):129-37. doi: 10.1097/00004836-198404000-00006.
The role of the anorectal band in the genesis of hemorrhoids is studied. The anorectal band is a fibroepithelial tube which is a remnant of the anorectal sinus. Seventy-six hemorrhoid patients and 32 controls were studied. Rectal neck pressure recording was done for all subjects. Two biopsies were taken from the lower rectal neck of each individual of the hemorrhoid and the control group, and were examined microscopically. Rectal neck pressure was measured in 67 patients of the hemorrhoid group after internal sphincterotomy. The mean rectal neck pressure in the hemorrhoid patients was significantly higher than the controls. Postoperative pressure measurement showed normal values. Microscopic examination of the rectal neck specimens revealed the presence of fibrous bands in the lower rectal neck submucosa of all hemorrhoid patients and in only one control subject. Evidence suggests that this fibrous band is the anorectal band which is an embryonic vestige. A new theory of the pathogenesis of hemorrhoids is presented. Evidence in support of the theory is also shown. The treatment of hemorrhoids in view of this theory is discussed.
研究了肛管直肠环在痔疮发生中的作用。肛管直肠环是一个纤维上皮管,是肛管直肠窦的残余物。对76例痔疮患者和32例对照者进行了研究。对所有受试者进行直肠颈部压力记录。从痔疮组和对照组的每个个体的直肠下段颈部取两块活检组织,并进行显微镜检查。对67例痔疮组患者在内括约肌切断术后测量直肠颈部压力。痔疮患者的平均直肠颈部压力显著高于对照组。术后压力测量显示值正常。对直肠颈部标本的显微镜检查发现,所有痔疮患者的直肠下段颈部黏膜下层均存在纤维带,而对照组中只有1例存在。有证据表明,这条纤维带就是作为胚胎遗迹的肛管直肠环。提出了一种新的痔疮发病机制理论。还展示了支持该理论的证据。并讨论了基于该理论的痔疮治疗方法。