Kyono K, Tsuiki A, Mori R, Momono K, Nagaike F, Imaizumi H, Saito A, Hoshi K, Hoshiai H
Nihon Sanka Fujinka Gakkai Zasshi. 1984 Apr;36(4):503-7.
The relation among ultrasonographic follicular diameter, serum estradiol (E2), luteinizing hormone (LH), cervical mucus changes, and basal body temperature (BBT) was studied. One hundred and eight cycles were examined in forty-two infertile patients. The last low day of the BBT curve was taken as day zero. In 83 of the 85 cycles, 158 of 163 times, follicles could be observed by ultrasonography. Follicular rupture was confirmed in 12 cycles. The mean diameter of the follicles measured the day before estimated ovulation was 24.00 +/- 3.10mm (mean +/- S.D.). Serum E2 levels were more than 400pg /ml from day -2 to day -1 and the peak serum LH levels occurred on day 0. The volume of cervical mucus (C.M.) was more than 100mm3 from day -2 to day +1. The volume was decreased in clomid stimulated cycles and the C.M. displayed a 3+ ferning 23/28 cycles on day 0. Among 5 pregnancies induced by homologous artificial insemination (AIH), three were done on day -2, one on day +1 and one on day +2. The best time to do AIH is when serum E2 is more than 400pg /ml, serum LH is more than 60m IU/ml, cervical mucus is 3+ ferning , and the follicular diameter is more than 20mm.
研究了超声卵泡直径、血清雌二醇(E2)、促黄体生成素(LH)、宫颈黏液变化与基础体温(BBT)之间的关系。对42例不孕患者的108个周期进行了检查。将BBT曲线的最后一个低温日作为第0天。在85个周期中的83个周期、163次中的158次,通过超声可观察到卵泡。12个周期证实有卵泡破裂。预计排卵前一天测量的卵泡平均直径为24.00 +/- 3.10mm(平均值 +/- 标准差)。从第-2天到第-1天血清E2水平超过400pg/ml,血清LH峰值出现在第0天。从第-2天到第+1天宫颈黏液(C.M.)量超过100mm3。在克罗米芬刺激的周期中黏液量减少,且在第0天C.M.在28个周期中有23个周期显示为3级羊齿状结晶。在5例通过同种人工授精(AIH)诱导的妊娠中,3例在第-2天进行,1例在第+1天进行,1例在第+2天进行。进行AIH的最佳时间是血清E2超过400pg/ml、血清LH超过60mIU/ml、宫颈黏液为3级羊齿状结晶且卵泡直径超过20mm时。