Khan A R, Iyer B V, Cirelli R A, Vasavada R C
J Pharm Sci. 1984 Mar;73(3):302-5. doi: 10.1002/jps.2600730305.
Lanolin alcohols-ethylcellulose films were investigated as a potential drug delivery system for the controlled release of salicylic acid. The effects of changes in film composition, drug concentration, drug solubility, and stirrer speed on the in vitro release of salicylic acid have been examined. The drug release has been found to obey a diffusion-controlled matrix model and square root of time release profile both in the suspension and solution cases.
羊毛脂醇-乙基纤维素膜作为水杨酸控释的潜在药物递送系统进行了研究。考察了膜组成、药物浓度、药物溶解度和搅拌速度的变化对水杨酸体外释放的影响。发现在悬浮液和溶液情况下，药物释放均符合扩散控制的基质模型和时间平方根释放曲线。
