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[猪降钙素对癌性骨破坏所致疼痛的影响]

[Effect of porcine calcitonin on pain caused by cancer-induced bone destruction].

作者信息

Egawa J, Kawada Y, Abe M, Miki H, Fujinuma A, Utsunomia Y, Kawano H, Kawaguchi H, Kuroiwa S, Saito A

出版信息

Gan No Rinsho. 1984 Mar;30(3):251-8.

PMID:6716657
Abstract

The analgesic effect of porcine calcitonin (PCT) was studied in 32 patients with cancer-induced bone destruction. Twenty patients (62.5%) showed some response among them 10 of 13 patients who had suffered from uncontrollable pain despite other treatment methods such as radiotherapy, and or the administration of other analgesics. The effect was observed about 10 days after the administration of the drug. Combined therapy with PCT and other modalities such as radiotherapy, chemotherapy and hormone therapy had a marked effect in controlling the pain.

摘要

对32例癌症所致骨破坏患者研究了猪降钙素(PCT)的镇痛效果。20例患者(62.5%)出现了一定反应,其中13例尽管接受了放疗和/或使用其他镇痛药等其他治疗方法但仍有难以控制的疼痛,这13例中有10例出现了反应。用药后约10天观察到了效果。PCT与放疗、化疗和激素治疗等其他方式联合治疗在控制疼痛方面有显著效果。

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