Jose B, Perkins L P, Kays H, Chu A M, Sharma S C
J Surg Oncol. 1984 Apr;25(4):250-1. doi: 10.1002/jso.2930250406.
This study is a review of 39 patients with testicular seminoma, Stage I, treated at the Department of Radiation Oncology, James Graham Brown Cancer Center from 1959 to 1978. The age of the patients ranged from 16 to 70 years with a median of 37. Thirty-two (82%) patients presented with swelling or mass in the testis, four patients with pain, and three patients had seminoma diagnosed incidentally. Twenty (51%) patients had the tumor on the right side and 19 (49%) patients had the tumor on the left side. All patients received irradiation to the ipsilateral inguinal, iliac, and bilateral para-aortic nodes with "hockey stick" type fields. The majority of the patients received a midplane dose of 3,200 to 3,600 rad in 3-4 weeks time. None of the patients received prophylactic irradiation to the mediastinum and supraclavicular region. The 5-year actuarial survival rate is 96%. There is no additional benefit in giving prophylactic irradiation to the mediastinum and supraclavicular regions in Stage I testicular seminoma. A brief review of the literature regarding the role of prophylactic irradiation in this group of patients is done.
本研究回顾了1959年至1978年在詹姆斯·格雷厄姆·布朗癌症中心放射肿瘤学系接受治疗的39例I期睾丸精原细胞瘤患者。患者年龄在16岁至70岁之间，中位数为37岁。32例（82%）患者表现为睾丸肿胀或肿块，4例患者有疼痛症状，3例患者为偶然诊断出精原细胞瘤。20例（51%）患者肿瘤位于右侧，19例（49%）患者肿瘤位于左侧。所有患者均接受了同侧腹股沟、髂血管和双侧腹主动脉旁淋巴结的“曲棍球棒”型野照射。大多数患者在3 - 4周内接受的中平面剂量为3200至3600拉德。没有患者接受纵隔和锁骨上区域的预防性照射。5年精算生存率为96%。对于I期睾丸精原细胞瘤患者，对纵隔和锁骨上区域进行预防性照射并无额外益处。本文对关于预防性照射在这组患者中的作用的文献进行了简要回顾。
