• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Accelerated onset of viral transcription in adenovirus-infected HeLa cells treated with the tumor promoter 12-O-tetradecanoyl-phorbol-13-acetate.在用肿瘤启动子12 - O - 十四烷酰佛波醇 - 13 - 乙酸酯处理的腺病毒感染的HeLa细胞中病毒转录的加速起始。
Mol Cell Biol. 1984 Mar;4(3):563-6. doi: 10.1128/mcb.4.3.563-566.1984.
2
Induction of integrated adenovirus E1A and E1B genes in transformed human cells by phorbol ester tumor promoters.佛波酯肿瘤启动子诱导转化人细胞中整合的腺病毒E1A和E1B基因。
Cancer Res. 1987 Feb 1;47(3):803-8.
3
Adenovirus early region 3 promoter regulation by E1A/E1B is independent of alterations in DNA binding and gene activation of CREB/ATF and AP1.腺病毒早期区域3启动子受E1A/E1B的调控独立于CREB/ATF和AP1的DNA结合及基因激活的改变。
J Virol. 1990 May;64(5):2004-13. doi: 10.1128/JVI.64.5.2004-2013.1990.
4
Effects of 12-O-tetradecanoylphorbol-13-acetate on the incorporation of labelled precursors into RNA, DNA and protein in epidermis, dermis and subcutis from precancerous mouse skin with reference to enhanced tumorigenesis.12-O-十四烷酰佛波醇-13-乙酸酯对癌前小鼠皮肤的表皮、真皮和皮下组织中标记前体掺入RNA、DNA和蛋白质的影响及其与肿瘤发生增强的关系
Carcinogenesis. 1984 Feb;5(2):135-41. doi: 10.1093/carcin/5.2.135-a.
5
Involvement of topoisomerases in replication, transcription, and packaging of the linear adenovirus genome.拓扑异构酶参与线性腺病毒基因组的复制、转录和包装。
J Virol. 1990 Feb;64(2):691-9. doi: 10.1128/JVI.64.2.691-699.1990.
6
Antagonistic action of retinoic acid against teleocidin and 12-O-tetradecanoyl-phorbol-13-acetate on activation of Epstein-Barr virus genomes.维甲酸对杀鱼菌素和十四酰佛波醇乙酯激活爱泼斯坦-巴尔病毒基因组的拮抗作用。
Carcinogenesis. 1984 Apr;5(4):483-7. doi: 10.1093/carcin/5.4.483.
7
The state of cellular differentiation determines the activity of the adenovirus E1A enhancer element: evidence for negative regulation of enhancer function.细胞分化状态决定腺病毒E1A增强子元件的活性：增强子功能负调控的证据。
J Virol. 1990 Jan;64(1):161-72. doi: 10.1128/JVI.64.1.161-172.1990.
8
Radiomimetic activity of phorbol esters exerted in HeLa cells in comparison with their tumor-promoting capacity.佛波酯在HeLa细胞中发挥的拟放射性活性与其促肿瘤能力的比较。
Cancer Res. 1984 Jan;44(1):139-43.
9
12-O-tetradecanoylphorbol-13-acetate actions on macromolecular synthesis, ornithine decarboxylase, and cellular differentiation of the rat embryonic visceral yolk sac in culture.12-O-十四烷酰佛波醇-13-乙酸酯对培养的大鼠胚胎内脏卵黄囊大分子合成、鸟氨酸脱羧酶及细胞分化的作用
Cancer Res. 1983 Nov;43(11):5552-9.
10
Tumor promoters alter the temporal program of adenovirus replication in human cells.肿瘤启动子改变了腺病毒在人类细胞中的复制时间程序。
Mol Cell Biol. 1981 Apr;1(4):370-80. doi: 10.1128/mcb.1.4.370-380.1981.

引用本文的文献

1
PMA induces expression from the herpes simplex virus thymidine kinase promoter via the activation of JNK and ERK in the presence of adenoviral E1A proteins.在腺病毒E1A蛋白存在的情况下，佛波酯通过激活JNK和ERK诱导单纯疱疹病毒胸苷激酶启动子的表达。
Arch Biochem Biophys. 2009 Oct 15;490(2):145-57. doi: 10.1016/j.abb.2009.08.013. Epub 2009 Aug 23.
2
Identification of a region on the adenovirus E1A gene responsible for induction by phorbol ester tumor promoter.鉴定腺病毒E1A基因上一个负责被佛波酯肿瘤启动子诱导的区域。
In Vitro Cell Dev Biol Anim. 2001 Jul-Aug;37(7):465-70. doi: 10.1290/1071-2690(2001)037<0465:IOAROT>2.0.CO;2.
3
Adenovirus E1A coding sequences that enable ras and pmt oncogenes to transform cultured primary cells.能使ras和pmt癌基因转化培养原代细胞的腺病毒E1A编码序列。
Mol Cell Biol. 1986 Mar;6(3):887-99. doi: 10.1128/mcb.6.3.887-899.1986.
4
A DNA-activated protein kinase from HeLa cell nuclei.一种来自海拉细胞核的DNA激活蛋白激酶。
Mol Cell Biol. 1990 Dec;10(12):6460-71. doi: 10.1128/mcb.10.12.6460-6471.1990.

本文引用的文献

1
Sedimentation characteristics of rapidly labelled RNA from HeLa cells.来自海拉细胞的快速标记RNA的沉降特性。
Biochem Biophys Res Commun. 1962 Jun 4;7:486-90. doi: 10.1016/0006-291x(62)90341-8.
2
Control of adenovirus early gene expression: posttranscriptional control mediated by both viral and cellular gene products.腺病毒早期基因表达的调控：由病毒和细胞基因产物介导的转录后调控。
Mol Cell Biol. 1981 Sep;1(9):807-13. doi: 10.1128/mcb.1.9.807-813.1981.
3
Mechanism of activation of early viral transcription by the adenovirus E1A gene product.腺病毒E1A基因产物激活早期病毒转录的机制。
Cell. 1981 Oct;26(2 Pt 2):213-20. doi: 10.1016/0092-8674(81)90304-4.
4
Induction of specific protein synthesis by phorbol esters in mouse epidermal cell culture.佛波酯在小鼠表皮细胞培养中诱导特异性蛋白质合成
Cancer Res. 1981 Jun;41(6):2025-31.
5
Isolation of type 5 adenovirus mutants with a cold-sensitive host range phenotype: genetic evidence of an adenovirus transformation maintenance function.具有冷敏感宿主范围表型的5型腺病毒突变体的分离：腺病毒转化维持功能的遗传学证据。
Virology. 1982 Oct 15;122(1):109-24. doi: 10.1016/0042-6822(82)90381-6.
6
Regulation of gene expression by tumor promoters. III. Complementation of the developmental program in myeloid leukemic cells by regulating mRNA production and mRNA translation.
Int J Cancer. 1981 Nov 15;28(5):615-20. doi: 10.1002/ijc.2910280514.
7
Epidermal growth factor, like tumor promoters, enhances viral and radiation-induced cell transformation.表皮生长因子与肿瘤启动子一样，可增强病毒和辐射诱导的细胞转化。
Carcinogenesis. 1981;2(3):183-7. doi: 10.1093/carcin/2.3.183.
8
Tumor promoters alter the temporal program of adenovirus replication in human cells.肿瘤启动子改变了腺病毒在人类细胞中的复制时间程序。
Mol Cell Biol. 1981 Apr;1(4):370-80. doi: 10.1128/mcb.1.4.370-380.1981.
9
Tumor promoters increase the synthesis of a 32,000-dalton protein in BALB/c 3T3 cells.肿瘤启动子可增加BALB/c 3T3细胞中一种32000道尔顿蛋白质的合成。
Proc Natl Acad Sci U S A. 1982 Mar;79(6):1800-4. doi: 10.1073/pnas.79.6.1800.
10
Regulation of early adenovirus transcription: a protein product of early region 2 specifically represses region 4 transcription.早期腺病毒转录的调控：早期区域2的一种蛋白质产物特异性抑制区域4的转录。
Proc Natl Acad Sci U S A. 1980 Apr;77(4):1893-7. doi: 10.1073/pnas.77.4.1893.

在用肿瘤启动子12 - O - 十四烷酰佛波醇 - 13 - 乙酸酯处理的腺病毒感染的HeLa细胞中病毒转录的加速起始。

Accelerated onset of viral transcription in adenovirus-infected HeLa cells treated with the tumor promoter 12-O-tetradecanoyl-phorbol-13-acetate.

作者信息

Carter T H, Milovanovic Z Z, Babiss L E, Fisher P B

出版信息

Mol Cell Biol. 1984 Mar;4(3):563-6. doi: 10.1128/mcb.4.3.563-566.1984.

DOI:10.1128/mcb.4.3.563-566.1984
PMID:6717433
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC368737/
Abstract

When adenovirus type 5-infected HeLa cells were exposed to the tumor promoter 12-O-tetradecanoyl-phorbol-13-acetate, short pulse-labeling with [3H]uridine in vivo and [3H]UTP incorporation by isolated nuclei in vitro were both consistent with a decreased latent period before initiation by RNA polymerase at early viral promoters. Acceleration was not dependent upon concurrent protein synthesis and could not be attributed to rapid entry of virus into the cell nucleus. 12-O-tetradecanoyl-phorbol-13-acetate suppressed the transcription-delay phenotype of the E1a mutant, hr1, without restoring its ability to replicate.

摘要

当用5型腺病毒感染的HeLa细胞暴露于肿瘤启动子12 - O - 十四烷酰佛波醇 - 13 - 乙酸酯时，体内用[3H]尿苷进行的短脉冲标记以及体外分离细胞核中[3H]UTP的掺入，均与早期病毒启动子处RNA聚合酶起始前潜伏期缩短一致。加速并不依赖于同时进行的蛋白质合成，也不能归因于病毒快速进入细胞核。12 - O - 十四烷酰佛波醇 - 13 - 乙酸酯抑制了E1a突变体hr1的转录延迟表型，但未恢复其复制能力。