Zuffa M, Kubancok J, Rusnák I, Mensatoris K, Horváth A
Neoplasma. 1984;31(2):231-6.
During the period of 1963-1982 we treated at our hospital 1694 patients with diagnosed internal malignancies. Of them, paraneoplastic syndrome as the first manifestation of the disease was found in 127 (7.4%). In 79 patients (4.6%) this first symptoms has also been an early manifestation of the malignoma (good general condition, without typical clinical symptoms of cancer). The paraneoplastic syndrome as the first symptom of the disease was manifested mainly as rheumatologic (58 patients; 3.4%) and thrombophlebitis (33 patients; 1.9%) symptoms. While thrombophlebitis as the first symptom of the disease was at the same time only in 48% also an early symptom, rheumatologic syndromes were also early symptoms in as many as 74% of cases. Hemoblastoses, lymphomas, and plasmacytomas are diseases which were accompanied by a paraneoplastic syndrome not only as the first but also as an early manifestation of the disease.
在1963年至1982年期间，我们医院收治了1694例确诊为内部恶性肿瘤的患者。其中，副肿瘤综合征作为疾病的首发表现见于127例（7.4%）。在79例患者（4.6%）中，这一首发症状也是恶性肿瘤的早期表现（一般状况良好，无典型癌症临床症状）。副肿瘤综合征作为疾病的首发症状主要表现为风湿性症状（58例；3.4%）和血栓性静脉炎（33例；1.9%）。血栓性静脉炎作为疾病的首发症状时，同时仅有48%也是早期症状，而风湿性综合征在多达74%的病例中也是早期症状。成血细胞增多症、淋巴瘤和浆细胞瘤等疾病不仅在疾病首发时伴有副肿瘤综合征，在疾病早期也伴有该综合征。
