脑多巴胺耗竭性损伤大鼠给予2-脱氧-D-葡萄糖后的血浆代谢物
Plasma metabolites after 2-deoxy-D-glucose in rats with brain dopamine-depleting lesions.
作者信息
Rowland N, Bales A
出版信息
Physiol Behav. 1984 Jan;32(1):155-7. doi: 10.1016/0031-9384(84)90090-8.
PMID:6718528
Abstract
Rats with selective brain dopamine-depleting lesions produced by 6-hydroxydopamine failed to increase their food intake after 2-deoxy-D-glucose administration. Their hyperglycemic response to 2DG was identical to that of intact controls. Neither group showed significant mobilization of free fatty acids or production of ketones.
摘要
用6-羟基多巴胺造成选择性脑多巴胺耗竭性损伤的大鼠，在给予2-脱氧-D-葡萄糖后未能增加其食物摄入量。它们对2-脱氧-D-葡萄糖的高血糖反应与完整对照组相同。两组均未显示出游离脂肪酸的显著动员或酮的产生。
Zotero 插件