雌激素对去卵巢、部分肝切除大鼠食物摄入量和体重的影响。

Estrogen-induced effects on food intake and body weight in ovariectomized, partially lipectomized rats.

作者信息

Gavin M L, Gray J M, Johnson P R

出版信息

Physiol Behav. 1984 Jan;32(1):55-9. doi: 10.1016/0031-9384(84)90070-2.

Abstract

Following ovariectomy, rats were either partially lipectomized (10-15% of total body lipid was removed) or left intact, and were treated with either sesame oil vehicle or estradiol benzoate (EB; 4 micrograms/day) for 2 weeks. Although lipectomy resulted in a change in carcass adiposity, robust behavioral and metabolic effects of EB were observed in all animals. EB treatment induced changes in all carcass components examined, including lipid, protein and water. Lipid:protein ratios were not altered by EB treatment.

摘要

卵巢切除术后，大鼠要么进行部分脂肪切除术（去除全身脂质的10 - 15%），要么保持完整，并用芝麻油载体或苯甲酸雌二醇（EB；4微克/天）处理2周。尽管脂肪切除术导致了胴体肥胖的变化，但在所有动物中都观察到了EB强大的行为和代谢效应。EB处理引起了所有检测的胴体成分的变化，包括脂质、蛋白质和水分。EB处理未改变脂质与蛋白质的比例。