Bennion R S, Wilson S E, Serota A I, Williams R A
Rev Infect Dis. 1984 Mar-Apr;6 Suppl 1:S132-8. doi: 10.1093/clinids/6.supplement_1.s132.
Mesenteric ischemia is a catastrophic event, which has a mortality due to florid sepsis that approaches 100%. The demography of the bacterial changes has not been documented. After 72 hr of colonic ischemia in the dog, the total number of anaerobic organisms increased while the number of aerobic organisms decreased. After 24 hr of ischemia, anaerobic bacteria appeared only in the portal vein and persisted. Cultures of peritoneal fluid and aortic blood became positive for the same anaerobic organisms after 48 hr. Acute colonic ischemia promotes a relative overgrowth of intraluminal anaerobic bacteria, which progressively invade the portal vein and later the systemic circulation.
肠系膜缺血是一种灾难性事件,因严重脓毒症导致的死亡率接近100%。细菌变化的人口统计学情况尚无文献记载。犬结肠缺血72小时后,厌氧生物总数增加,而需氧生物数量减少。缺血24小时后,厌氧细菌仅出现在门静脉并持续存在。48小时后,腹膜液和主动脉血培养出相同的厌氧生物呈阳性。急性结肠缺血促使肠腔内厌氧细菌相对过度生长,这些细菌逐渐侵入门静脉,随后进入体循环。