Amato M, Ruckstuhl C, von Muralt G
Schweiz Med Wochenschr. 1984 Mar 24;114(12):412-4.
Bacterial infections are more frequent and severe in the first few days of life than at any time thereafter. It is also well recognized that in newborn infants clinical signs of infection may be minimal: accordingly, laboratory tests are of greatest importance for diagnosis in this period of life. Because of the difficulties in interpreting the meaning of granulocyte changes in preterm infants, we have examined the possible clinical usefulness of serum c-reactive protein, determined by a new, sensitive electrophoretic method (ZIA), for detection of bacterial infection in infants of this age. This study suggests that c-reactive protein testing is a helpful adjunct in diagnosing bacterial infection in the first month of life.
细菌感染在出生后的头几天比之后的任何时候都更频繁、更严重。人们也充分认识到，新生儿的感染临床症状可能很轻微：因此，实验室检查在这个生命阶段的诊断中最为重要。由于难以解读早产儿粒细胞变化的意义，我们采用一种新的、灵敏的电泳方法（ZIA）测定血清C反应蛋白，以检验其在检测该年龄段婴儿细菌感染方面可能的临床实用性。这项研究表明，C反应蛋白检测有助于诊断出生后第一个月内的细菌感染。
