Korkuschko O W, Iwanow L A, Sarkissow K G
Z Gerontol. 1984 Jan-Feb;17(1):39-44.
The studies involved practically healthy subjects aged 20-102. The oscillogram and rheogram were recorded in the upper and lower extremities. Measurements on the pulse wave progagation velocity and the skin capillary blood circulation were taken. The oxygen tension in subcutaneous cellular tissue was determined by the polarographic method. It was found that the values of systolic pressure, pulse pressure, and mean dynamic pressure increased, whereas the oscillographic index decreased with aging. In older people the rheogram was characterized by a slow elevation, rounded peak, frequently arch-shaped, flattening or absence of diastolic wave, shortening of Q-X-interval, and decrease of rheographic index. These age-associated changes reflecting decrease in elasticity and increase in rigidity of peripheral arteries as well as decrease in blood filling of tissues were more pronounced in the lower extremities. In older people the oxygen supply and the intensity of tissue respiration in subcutaneous cell tissue of legs were lower as compared with the upper extremities. In young adults no differences were found in oscillographic, rheographic, and polarographic values as well as in capillaroscopic pictures between upper and lower extremities.
这些研究涉及年龄在20至102岁之间的几乎健康的受试者。记录了上肢和下肢的示波图和血流图。测量了脉搏波传播速度和皮肤毛细血管血液循环。用极谱法测定皮下细胞组织中的氧张力。结果发现，收缩压、脉压和平均动态压力值随年龄增长而升高，而示波指数随年龄增长而降低。老年人的血流图特征为上升缓慢、峰值圆润、常呈拱形、舒张波变平或消失、Q-X间期缩短以及血流图指数降低。这些与年龄相关的变化反映了外周动脉弹性降低和僵硬程度增加以及组织血液充盈减少，在下肢更为明显。与上肢相比，老年人腿部皮下细胞组织的氧气供应和组织呼吸强度较低。在年轻人中，上肢和下肢在示波、血流图和极谱值以及毛细血管镜图像方面未发现差异。
