Klimov A N, Petrova-Maslakova L G, Khechinashvili G G, Chkhatarashvili L M, Golikov Iu P
Kardiologiia. 1978 Jun;18(6):23-9.
A method for the delipidization of blood plasma of rabbits and dogs with diethyl ether with its subsequent reinfusion into the animal's body is described. Triglycerides and cholesterol were mainly extracted from blood plasma, and only 1/3 of phospholipids. In dog experiments the plasma delipidization procedures led to a decrease of the cholesterol content in the overall fraction of atherogenic lipoproteins of low and very low density and an increase of the cholesterol content in antiatherogenic lipoproteins of high density. The lipoextraction procedures are harmless and may be employed for reducing the blood lipid level.
本文描述了一种用乙醚对兔和犬的血浆进行脱脂处理并随后将其回输到动物体内的方法。甘油三酯和胆固醇主要从血浆中被提取出来，而磷脂仅提取了三分之一。在犬的实验中，血浆脱脂程序导致低密度和极低密度致动脉粥样硬化脂蛋白总组分中的胆固醇含量降低，而高密度抗动脉粥样硬化脂蛋白中的胆固醇含量增加。脂质提取程序是无害的，可用于降低血脂水平。
