Tsutsul'kovskaia M Ia, Minsker E I, Panteleeva G P, Beliaev B S, Piatnitskiĭ A N
Zh Nevropatol Psikhiatr Im S S Korsakova. 1984;84(3):387-93.
Multicentre international studies make it possible to amass rapidly and reliably the necessary amount of representative data allowing for the verification of the results obtained by different scientific schools. They also represent the most effective approach to the search for attaining the mutual understanding among specialists of different scientific schools and for the elaboration of uniform clinical outlooks . Guidelines were developed to be adhered to while organizing and conducting multicentre psychopharmacological studies. The authors describe the general scheme and the basic stages of a multicentre psychopharmacological study of leponex which involved specialists from ten centres from six countries (CSSR, GDR, HPR, PRB , PPR, USSR).
多中心国际研究能够迅速且可靠地积累必要数量的代表性数据,从而对不同科学流派所获得的结果进行验证。它们也是寻求不同科学流派的专家之间达成相互理解以及制定统一临床观点的最有效途径。在组织和开展多中心精神药理学研究时,制定了一些指南以供遵循。作者描述了一项氯氮平多中心精神药理学研究的总体方案和基本阶段,该研究涉及来自六个国家(捷克斯洛伐克社会主义共和国、德意志民主共和国、匈牙利人民共和国、波兰人民共和国、罗马尼亚人民共和国、苏联)十个中心的专家。