Monteiro-Riviere N A, Popp J A
Am J Anat. 1984 Jan;169(1):31-43. doi: 10.1002/aja.1001690103.
This ultrastructural study of the respiratory epithelium of the rat nasal mucosa revealed six morphologically distinct cell types: goblet cells, basal cells, ciliated cells, nonciliated columnar cells, cuboidal cells, and brush cells. The latter three have not been previously characterized in the rat nasal mucosa by transmission electron microscopy. Cuboidal cells observed on the conchae and lateral wall had short apical microvilli which were less dense than the microvilli of the nonciliated columnar cells. Nonciliated columnar cells also identified on the conchae and lateral wall had short microvilli and an extensive network of smooth endoplasmic reticulum in the apical region. The brush cell had distinct ultrastructural features; it was pear-shaped, with the broad base adjacent to the basement membrane and large microvilli on the surface. Microfilaments, microtubules, vesicles, and paired cisternae were found in the apical cytoplasm. Brush cells occurred singly on the conchae and lateral wall but were not identified in the respiratory epithelium of the nasal septum. These findings indicate the complexity of cell types composing the rat nasal respiratory epithelium.
杯状细胞、基底细胞、纤毛细胞、无纤毛柱状细胞、立方体细胞和刷状细胞。后三种细胞类型此前尚未通过透射电子显微镜在大鼠鼻黏膜中得到表征。在鼻甲和侧壁观察到的立方体细胞具有短的顶端微绒毛，其密度低于无纤毛柱状细胞的微绒毛。在鼻甲和侧壁也鉴定出的无纤毛柱状细胞具有短微绒毛，并且在顶端区域有广泛的滑面内质网网络。刷状细胞具有独特的超微结构特征；它呈梨形，宽基部与基底膜相邻，表面有大的微绒毛。在顶端细胞质中发现了微丝、微管、囊泡和成对的池。刷状细胞单独出现在鼻甲和侧壁上，但在鼻中隔的呼吸上皮中未被鉴定出。这些发现表明构成大鼠鼻呼吸上皮的细胞类型具有复杂性。
