从清醒犬的枕大池采集脑脊液的新方法。
New method for the collection of cerebrospinal fluid from the cisterna magna of conscious dogs.
作者信息
Suzuki H, Ferrario C M
出版信息
Am J Physiol. 1984 Apr;246(4 Pt 2):H551-8. doi: 10.1152/ajpheart.1984.246.4.H551.
Abstract
We have developed a catheter system than can be implanted chronically into the cisterna magna of the dog to obtain serial samples of cerebrospinal fluid (CSF) for up to 8 wk. A direct access to the CSF of the cisterna magna provided an opportunity to determine also base-line values of CSF sodium, potassium, norepinephrine, epinephrine, and angiotensin II immunoreactivity and compare relative differences in the concentration of these variables between the central and peripheral compartments.
摘要
我们已经开发出一种导管系统，可长期植入犬的枕大池，以获取长达8周的连续脑脊液（CSF）样本。直接获取枕大池的脑脊液，也为测定脑脊液钠、钾、去甲肾上腺素、肾上腺素和血管紧张素II免疫反应性的基线值，以及比较这些变量在中枢和外周区域浓度的相对差异提供了机会。
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