Igarashi M, Gilmartin R C, Gerald B, Wilburn F, Jabbour J T
Arch Neurol. 1984 May;41(5):531-5. doi: 10.1001/archneur.1984.04050170077022.
Twelve cases of large- and medium-sized cerebral artery stenosis and/or occlusion associated with bacterial meningitis occurred. Neurological complication due to arterial involvement developed in seven patients on the third and fourth days of illness; in one patient, it developed on the fifth day, and in another it developed on the 14th day. In three cases, this could not be determined. Arterial stenosis is considered primarily to result from arterial spasm due to humoral factors that may be elaborated within the CSF or arterial wall, as in the cases of ruptured aneurysm; and secondarily, from to inflammatory involvement of major vessels at the base of the brain and from irritation by angiographic contrast material.
发生了12例与细菌性脑膜炎相关的大脑中、大动脉狭窄和/或闭塞病例。7例患者在发病第3天和第4天出现因动脉受累导致的神经并发症；1例患者在第5天出现，另1例在第14天出现。3例情况无法确定。动脉狭窄主要被认为是由于脑脊液或动脉壁内可能产生的体液因素导致动脉痉挛所致，如同动脉瘤破裂的情况；其次，是由于大脑底部主要血管的炎症累及以及血管造影剂的刺激。
