Hartman D E, Vishwanat B
Arch Otolaryngol. 1984 Jun;110(6):394-7. doi: 10.1001/archotol.1984.00800320048011.
Primidone has been reported to be effective in reducing tremor in patients with benign essential tremor. There is at least one report that suggests that the medication may reduce voice tremor, a frequent component of the essential tremor syndrome. Three patients with spastic dysphonia of essential (voice) tremor and one with more typical essential (voice) tremor were treated with primidone and experienced no alleviation in the voice signs. The side effects experienced by all patients were consistent with those noted in previous reports. Primidone does not seem to be effective in treating essential voice tremor or spastic dysphonia of essential voice tremor.
据报道，扑米酮对减轻良性特发性震颤患者的震颤有效。至少有一份报告表明，该药物可能减轻语音震颤，这是特发性震颤综合征的常见症状。三名患有原发性（语音）震颤性痉挛性发声障碍的患者和一名患有更典型原发性（语音）震颤的患者接受了扑米酮治疗，但语音症状并未得到缓解。所有患者经历的副作用与先前报告中指出的一致。扑米酮似乎对治疗原发性语音震颤或原发性语音震颤性痉挛性发声障碍无效。
