从事木材防腐处理工作的工人的基因毒性暴露。
Genotoxic exposure of workers creosoting wood.
作者信息
Bos R P, Hulshof C T, Theuws J L, Henderson P T
出版信息
Br J Ind Med. 1984 May;41(2):260-2. doi: 10.1136/oem.41.2.260.
In a small wood preserving industry spot samples were taken from contaminated surfaces at several places and tested for mutagenicity. The results suggest that the application of a wipe test can give a first indication of occupational exposure to mutagenic and carcinogenic substances, particularly when exposure occurs more from skin contact than from inhalation. One of the pesticide chemicals used to preserve wood is the mutagenic creosote . It was found that mutagens appeared in the urine of rats after intraperitoneal administration of creosote . Despite these results, no increase in mutagenicity could be detected in the urine of creosote workers in relation to their work.
在一个小型木材防腐行业，从几个地方的污染表面采集了现场样本，并对其进行了致突变性测试。结果表明，擦拭测试的应用可以初步表明职业性接触致突变和致癌物质的情况，特别是当接触更多是通过皮肤接触而非吸入时。用于木材防腐的一种农药化学品是具有致突变性的杂酚油。研究发现，给大鼠腹腔注射杂酚油后，其尿液中出现了诱变剂。尽管有这些结果，但未检测到杂酚油工人尿液中的致突变性相对于其工作有增加。
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