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严重甲酚中毒所致急性海因茨小体贫血：红细胞单采术治疗成功

Acute Heinz-body anemia due to severe cresol poisoning: successful treatment with erythrocytapheresis.

作者信息

Côté M A, Lyonnais J, Leblond P F

出版信息

Can Med Assoc J. 1984 May 15;130(10):1319-22.

PMID:6722696
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1483498/
Abstract

A patient with massive intravascular Heinz-body hemolytic anemia associated with the presence of bizarre-looking erythrocytes following the oral ingestion of approximately 100 mL of "penetrating oil", a petroleum distillate containing 85% kerosene, 12% cresol and 2% surfactant, is described. He was treated successfully with immediate erythrocytapheresis and forced diuresis.

摘要

本文描述了一名患者，口服约100毫升“渗透油”（一种含有85%煤油、12%甲酚和2%表面活性剂的石油馏出物）后，出现大量血管内海因茨小体溶血性贫血，并伴有形态怪异的红细胞。该患者通过立即进行红细胞单采术和强制利尿成功治愈。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2c9/1483498/46d9a390081a/canmedaj00360-0080-d.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2c9/1483498/a00106116089/canmedaj00360-0080-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2c9/1483498/db02a0686525/canmedaj00360-0080-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2c9/1483498/de5636f8514a/canmedaj00360-0080-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2c9/1483498/46d9a390081a/canmedaj00360-0080-d.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2c9/1483498/a00106116089/canmedaj00360-0080-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2c9/1483498/db02a0686525/canmedaj00360-0080-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2c9/1483498/de5636f8514a/canmedaj00360-0080-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2c9/1483498/46d9a390081a/canmedaj00360-0080-d.jpg

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本文引用的文献

1
Lower nephron nephrosis due to concentrated Lysol vaginal douches: a report of two cases.因浓缩来苏尔阴道灌洗导致的下肾单位肾病：两例报告
Can Med Assoc J. 1961 Mar 11;84(10):549.
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Erythrocyte hemighosts: a hallmark of severe oxidative injury in vivo.
Br J Haematol. 1982 Apr;50(4):575-82. doi: 10.1111/j.1365-2141.1982.tb01957.x.
3
Drug-induced oxidative haemolysis.药物性氧化溶血
Clin Haematol. 1980 Oct;9(3):557-86.
4
Heinz-body anemia: "bite cell" variant--a light and electron microscopic study.海因茨小体细胞贫血：“咬痕细胞”变体——光镜和电镜研究
Am J Hematol. 1983 Sep;15(2):135-46. doi: 10.1002/ajh.2830150205.
5
[Typhic and ileal perforations].
Med Trop (Mars). 1971 Jul-Aug;31(4):417-25.
6
[Acute poisoning by a domestic antiseptic: Cresyl].[一种家用防腐剂中毒：甲酚]
Mars Med. 1971;108(6):425-31.
7
[A case of severe cresol poisoning].[一例严重甲酚中毒病例]
Sem Hop. 1968 Nov 26;44(49):3029-31.
8
Methemoglobinemia, Heinz bodies, and acute massive intravascular hemolysis in lysol poisoning.来苏尔中毒导致的高铁血红蛋白血症、海因茨小体和急性大量血管内溶血。
Blood. 1971 Dec;38(6):739-44.
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Heinz body hemolytic animea. "Bite cells" -a clue to diagnosis.
Arch Intern Med. 1976 Feb;136(2):153-5. doi: 10.1001/archinte.136.2.153.