Leighton F A, Peakall D B, Butler R G
Science. 1983 May 20;220(4599):871-3. doi: 10.1126/science.6844918.
Hemolytic anemia developed in young herring gulls and Atlantic puffins given daily oral doses of a Prudhoe Bay crude oil. Anemia developed 4 to 5 days after the initiation of oil ingestion and was accompanied by Heinz-body formation and a strong regenerative response. The data evince a toxic effect on circulating red blood cells involving an oxidative biochemical mechanism and the first clear evidence of a primary mechanism of toxicity from the ingestion of crude oil by birds.
给幼年银鸥和大西洋海雀每日口服普拉德霍湾原油后，它们出现了溶血性贫血。在开始摄入原油4至5天后出现贫血，并伴有海因茨小体形成和强烈的再生反应。这些数据表明对循环红细胞有中毒作用，涉及氧化生化机制，这也是鸟类摄入原油导致中毒的首要机制的首个明确证据。
