Stĕpán J, Havránek T, Jelínková E, Straková M, Skrha J, Pacovský V
Experientia. 1984 May 15;40(5):517-8. doi: 10.1007/BF01952416.
The activity of intestinal isoenzyme of serum alkaline phosphatase was evaluated in 21 non-dialyzed patients with advanced renal failure and in 52 patients on regular hemodialysis. In patients without hepatopathy, a significant inverse correlation was found between the enzyme activity and serum calcium levels. Hepatopathy was the most significant variable influencing the enzyme activity in patients on dialysis. Secondary hyperparathyroidism and a decreased rate in enzyme elimination should be assessed for the above-normal activities of intestinal ALP in serum in chronic renal failure.
对21例未进行透析的晚期肾衰竭患者及52例定期进行血液透析的患者的血清碱性磷酸酶肠型同工酶活性进行了评估。在无肝病的患者中，发现该酶活性与血清钙水平之间存在显著的负相关。肝病是影响透析患者酶活性的最显著变量。对于慢性肾衰竭患者血清中肠碱性磷酸酶活性高于正常的情况，应评估继发性甲状旁腺功能亢进和酶清除率降低的情况。
