Rudas P, Pethes G
Gen Comp Endocrinol. 1984 Apr;54(1):154-61. doi: 10.1016/0016-6480(84)90211-9.
The possibility of conversion of L-thyroxine (T4) to L-3,5,3'-triiodothyronine (T3) and to 3,3',5'-triiodothyronine (reverse-T3, r-T3) has been investigated in chickens. Reverse-T3 could not be detected in normal animals. Both thyroidectomized and normal animals were able to convert exogenous T4 to T3. The administration of propylthiouracyl blocked this conversion to a greater extent than had been expected from the data on mammals. The conversion ratio is higher than in any other species reported in the literature. Data suggest that, as a result of the adaptation of the peripheral deiodination, thyroidectomized animals were able to convert more T4 to T3 than were normal ones.
已对鸡体内L-甲状腺素（T4）转化为L-3,5,3'-三碘甲状腺原氨酸（T3）以及3,3',5'-三碘甲状腺原氨酸（反式T3，r-T3）的可能性进行了研究。在正常动物中未检测到反式T3。甲状腺切除的动物和正常动物都能够将外源性T4转化为T3。给予丙硫氧嘧啶对这种转化的阻断程度比根据哺乳动物数据预期的更大。转化率高于文献中报道的任何其他物种。数据表明，由于外周脱碘的适应性变化，甲状腺切除的动物比正常动物能够将更多的T4转化为T3。
