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切除垂体和甲状腺的鸡暴露于轻度寒冷环境(10摄氏度)时甲状腺素向三碘甲状腺原氨酸转化的急性变化

Acute changes of the conversion of thyroxine to triiodothyronine in hypophysectomized and thyroidectomized chickens exposed to mild cold (10 degrees).

作者信息

Rudas P, Pethes G

出版信息

Gen Comp Endocrinol. 1986 Sep;63(3):408-13. doi: 10.1016/0016-6480(86)90140-1.

DOI:10.1016/0016-6480(86)90140-1
PMID:3557066
Abstract

The effect of acute cold (10 degrees) exposure on the tissue level of triiodothyronine (T3) and on the conversion of thyroxine (T4) to triiodothyronine, both in vitro and in vivo, has been investigated in young chickens previously thyroidectomized or hypophysectomized. It was found that cold exposure stimulates T4 to T3 conversion both in vivo and in vitro not only in intact animals but also in hypophysectomized and thyroidectomized ones. It is concluded that peripheral metabolism of thyroid hormones represents a self-standing but not sole route of adaptation to changes in environmental temperature.

摘要

在先前已进行甲状腺切除或垂体切除的幼鸡中,研究了急性冷暴露(10摄氏度)对三碘甲状腺原氨酸(T3)组织水平以及甲状腺素(T4)向三碘甲状腺原氨酸转化的影响,包括体内和体外的影响。结果发现,冷暴露不仅在完整动物中,而且在垂体切除和甲状腺切除的动物中,均能在体内和体外刺激T4向T3的转化。得出的结论是,甲状腺激素的外周代谢是适应环境温度变化的一个独立但非唯一途径。

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1
Acute changes of the conversion of thyroxine to triiodothyronine in hypophysectomized and thyroidectomized chickens exposed to mild cold (10 degrees).切除垂体和甲状腺的鸡暴露于轻度寒冷环境(10摄氏度)时甲状腺素向三碘甲状腺原氨酸转化的急性变化
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2
Effect of the exposure to cold on the extrathyroidal conversion of L-thyroxine to triiodo-L-thyronine, and on intramitochondrial alpha-glycerophosphate dehydrogenase activity in thyroidectomized rats on L-thyroxine.寒冷暴露对甲状腺切除并用L-甲状腺素治疗的大鼠甲状腺外L-甲状腺素向L-三碘甲状腺原氨酸转化以及线粒体内α-甘油磷酸脱氢酶活性的影响。
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Effects of thyroid hormones, antithyroid drugs and iodide on in vitro conversion of thyroxine to triiodothyronine.甲状腺激素、抗甲状腺药物及碘对甲状腺素体外转化为三碘甲状腺原氨酸的影响。
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