Hypertension. 1984 Mar-Apr;6(2 Pt 2):I198-206. doi: 10.1161/01.hyp.6.2_pt_2.i198.
Information on indices of coronary heart disease (CHD) and myocardial infarction (MI) (angina pectoris by Rose Questionnaire, MI by Rose Questionnaire, history, and electrocardiogram) was obtained in the Hypertension Detection and Follow-Up Program (U.S. National Institutes of Health) at baseline, Year 2, and Year 5 of follow-up. The presence of any of these findings at baseline markedly increased all-cause mortality during the 5 years of observation. In individuals with negative findings at baseline, the 5-year incidence of MI and angina pectoris by these indices was less in the Stepped Care than Referred Care cohort. These results are compatible with the conclusion that antihypertensive therapy reduces the incidence of symptomatic CHD.
在高血压检测与随访项目（美国国立卫生研究院）中，于随访的基线期、第2年和第5年获取了冠心病（CHD）和心肌梗死（MI）的相关指标信息（通过罗斯问卷评估心绞痛、通过罗斯问卷评估心肌梗死、病史以及心电图）。基线期出现这些发现中的任何一项，都会显著增加5年观察期内的全因死亡率。在基线期检查结果为阴性的个体中，与转诊护理队列相比，阶梯式护理队列中通过这些指标得出的MI和心绞痛的5年发病率更低。这些结果与抗高血压治疗可降低有症状CHD发病率的结论相符。
