Hodos W, Kuenzel W J
Invest Ophthalmol Vis Sci. 1984 Jun;25(6):652-9.
Two groups of 3-day-old broiler chicks were fitted over the right eye with plastic goggles that degraded the retinal image by producing spherical aberration, reduction of contrast, and blurring of edges. In one group of chicks, the goggles were hemispheric and affected the entire visual field. In the second group, the goggles only affected the frontal visual field. In both groups, the left eye was used as a control. A third group of chicks served as an untreated control group. After 3 weeks, the chicks were killed, the eyes removed, hemisected, and measured in the axial and equatorial planes. Because the avian eye is flattened in the equatorial plane, both sets of measurements are necessary in order to represent changes in its size and shape. The axial length of a laterally located avian eye is related to distance vision. The equatorial length is related to vision in the frontal field, which is used for near vision. For each group of chicks, the difference between the right eye and the left eye was compared. The treated eyes of the full- goggle group were significantly larger than their untreated eyes in both the axial and equatorial dimensions. The treated eyes of the frontal- goggle group differed only in the equatorial dimension. These results suggest that the increased equatorial length found after retinal-image degradation may serve as an animal model of myopia.
将两组3日龄的肉鸡雏鸡右眼戴上塑料眼罩，这些眼罩通过产生球差、降低对比度和模糊边缘来使视网膜图像退化。在一组雏鸡中，眼罩是半球形的，影响整个视野。在第二组中，眼罩只影响额视野。在两组中，左眼用作对照。第三组雏鸡作为未处理的对照组。3周后，将雏鸡处死，取出眼睛，切成两半，并在轴向和赤道平面进行测量。由于禽类眼睛在赤道平面是扁平的，因此需要这两组测量来表示其大小和形状的变化。横向禽类眼睛的轴向长度与远视力有关。赤道长度与额视野的视力有关，额视野用于近视力。对于每组雏鸡，比较右眼和左眼之间的差异。全眼罩组的处理眼在轴向和赤道维度上均显著大于未处理眼。额眼罩组的处理眼仅在赤道维度上有所不同。这些结果表明，视网膜图像退化后赤道长度增加可能作为近视的动物模型。
