Phat V N, Houissa-Vuong S, Baviera E, Schoonaert M F, Thévenon-Gonguet A M
J Gynecol Obstet Biol Reprod (Paris). 1984;13(1):31-4.
The authors report a case of endometrial stromal sarcoma which was detected by endometrial cytology. The tumour originates either in the stroma of the endometrium or in foci of myometrial adenomyosis. It occurs most frequently in patients who are more than 60 years of age. It appears as an intra-uterine polypoid mass and causes bleeding and pelvic pain. Its incidence is difficult to establish. Endometrial cytology is highly suggestive of stromal sarcoma when smears harbour numerous atypical sarcomatous cells mixed with regular endometrial cells. Biopsies of the endometrium show decidua-like arrangements of malignant cells. Stromal sarcoma constitutes the homologous form of mesenchymal tumours of the uterus. The prognosis depends on whether local recurrences occur and on the sites of metastases in which the sarcomatous component seems to be latent with lesions that resemble adenocarcinomata . The five years salvage rate is approximately 26 to 28%. Treatment is surgical with or without irradiation.
作者报告了一例通过子宫内膜细胞学检查发现的子宫内膜间质肉瘤病例。该肿瘤起源于子宫内膜间质或子宫肌层子宫腺肌病病灶。它最常发生于60岁以上的患者。表现为子宫内息肉样肿物,可引起出血和盆腔疼痛。其发病率难以确定。当涂片中有大量非典型肉瘤细胞与正常子宫内膜细胞混合时,子宫内膜细胞学高度提示间质肉瘤。子宫内膜活检显示恶性细胞呈蜕膜样排列。间质肉瘤是子宫间叶肿瘤的同源形式。预后取决于是否发生局部复发以及转移部位,其中肉瘤成分似乎在类似腺癌的病变中潜伏。五年挽救率约为26%至28%。治疗方法为手术,可联合或不联合放疗。