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宫颈锥切边缘在宫颈肿瘤患者管理中的意义。

Significance of cone biopsy margins in the management of patients with cervical neoplasia.

作者信息

Lubicz S, Ezekweche C, Allen A, Schiffer M

出版信息

J Reprod Med. 1984 Mar;29(3):179-84.

PMID:6726696
Abstract

Too many patients in the United States undergo hysterectomy for cervical neoplasia following cone biopsy because too many gynecologists choose not to pay attention to the pathology present at the margins of the cone specimen. In view of the need to improve the management of cervical neoplasia--i.e., to reduce the number of needless hysterectomies--a retrospective study was done to verify the trend in our institution and to evaluate the utilization of cone biopsy to determine the extent of the process. Also, the methods used for procuring the cone sample and for interpreting the results of the biopsy were studied. The present study included 345 patients who underwent a cone biopsy; subsequently, 102 of them had a hysterectomy. Based on the evaluation of the cases in this study, information was obtained about the performance of cone biopsy and the guidelines for determining when a hysterectomy should be performed and when other, less drastic means of eradicating the neoplasia should be considered.

摘要

在美国,太多接受宫颈锥形活检后患有宫颈肿瘤的患者接受了子宫切除术,因为太多妇科医生选择不关注锥形标本边缘存在的病理情况。鉴于改善宫颈肿瘤管理的必要性——即减少不必要的子宫切除数量——我们进行了一项回顾性研究,以核实我们机构的趋势,并评估锥形活检在确定病情程度方面的应用情况。此外,还研究了获取锥形样本和解读活检结果所使用的方法。本研究纳入了345例行锥形活检的患者;随后,其中102人接受了子宫切除术。基于对本研究中病例的评估,获得了有关锥形活检的实施情况以及确定何时应进行子宫切除术以及何时应考虑其他不太激进的肿瘤根除方法的指导原则的信息。

相似文献

1
Significance of cone biopsy margins in the management of patients with cervical neoplasia.宫颈锥切边缘在宫颈肿瘤患者管理中的意义。
J Reprod Med. 1984 Mar;29(3):179-84.
2
Adenocarcinoma in situ of the uterine cervix.子宫颈原位腺癌
Obstet Gynecol. 1992 Dec;80(6):935-9.
3
Accuracy of the diagnosis in suspected intraepithelial neoplasia of the cervix.宫颈疑似上皮内瘤变诊断的准确性。
Ann Chir Gynaecol. 1984;73(1):45-9.
4
Cervical cone margins as a predictor for residual dysplasia in post-cone hysterectomy specimens.宫颈锥切边缘作为锥切术后子宫切除标本中残余发育异常的预测指标。
Obstet Gynecol. 1994 Nov;84(5):898.
5
Endometrial and endocervical curettage findings at the time of cervical conization.宫颈锥切术时子宫内膜及宫颈管刮除术的检查结果
J Reprod Med. 1987 Feb;32(2):99-102.
6
Adenocarcinoma in situ of the cervix: management and outcome.宫颈原位腺癌:管理与结局
Gynecol Oncol. 1999 Jun;73(3):348-53. doi: 10.1006/gyno.1999.5395.
7
Conservative management of intraepithelial cervical neoplasia.宫颈上皮内瘤变的保守治疗
Can Med Assoc J. 1977 Mar 19;116(6):641-3.
8
[Cervical conization in dysplasia and carcinoma in situ. Role of concomitant uterine curettage].[宫颈发育异常和原位癌的宫颈锥切术。同期子宫刮宫术的作用]
Rev Fr Gynecol Obstet. 1994 Dec;89(12):602-5.
9
Management of patients with positive margins after cervical conization.宫颈锥切术后切缘阳性患者的管理
Obstet Gynecol. 1993 Sep;82(3):440-3.
10
Endocervical curettage, cone margins, and residual adenocarcinoma in situ of the cervix.宫颈管搔刮术、宫颈锥切切缘与宫颈原位腺癌残留
Obstet Gynecol. 1997 Jul;90(1):1-6. doi: 10.1016/S0029-7844(97)00122-1.

引用本文的文献

1
Predicting persistent/recurrent disease in the cervix after excisional biopsy.预测切除活检后宫颈持续性/复发性疾病。
MedGenMed. 2007 Apr 30;9(2):24.
2
The value of endocervical curettage at time of cervical cone biopsy.宫颈锥切活检时宫颈管搔刮术的价值。
J Natl Med Assoc. 1993 Feb;85(2):117-9.