Schmut O, Fellinger C, Hofmann H
Klin Monbl Augenheilkd. 1984 Mar;184(3):206-7. doi: 10.1055/s-2008-1054444.
Determination of glycosylated hemoglobins HbA1 or HbA1c by column chromatography is used for long-term glucose control. In the study reported here the authors compared the advantages and disadvantages of this new method and tried to show the importance of these determinations for patients with eye diseases. In a control group (blood glucose less than 120 mg/dl) HbA1-values of 6.5 +/- 1.2% and HbA1c-values of 4.4 +/- 0.5% were found. Well-controlled diabetics (blood glucose 80-180 mg/dl) had an HbA1 of 8.1 +/- 1.6% and an HbA1c of 5.8 +/- 1.1%, while diabetics with poor control (blood glucose 160-420 mg/dl) had an HbA1 of 10.6 +/- 2.1% and an HbA1c of 7.7 +/- 1.7%. HbA1 and HbA1c, respectively, should be measured in addition to blood glucose determination and oral glucose tolerance test.
采用柱色谱法测定糖化血红蛋白HbA1或HbA1c可用于长期血糖控制。在本文报道的研究中，作者比较了这种新方法的优缺点，并试图阐明这些测定对眼病患者的重要性。在一个对照组（血糖低于120mg/dl）中，发现HbA1值为6.5±1.2%，HbA1c值为4.4±0.5%。血糖控制良好的糖尿病患者（血糖80 - 180mg/dl）的HbA1为8.1±1.6%，HbA1c为5.8±1.1%，而血糖控制不佳的糖尿病患者（血糖160 - 420mg/dl）的HbA1为10.6±2.1%，HbA1c为7.7±1.7%。除了测定血糖和口服葡萄糖耐量试验外，还应分别测定HbA1和HbA1c。
