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[激发试验在慢性胰腺炎诊断中的意义(作者译)]

[The significance of the evocative test in the diagnosis of chronic pancreatitis (author's transl)].

作者信息

Sommer H, Kasper H, Fleischer K

出版信息

Med Klin. 1978 Jul 14;73(28-29):1051-5.

PMID:672758
Abstract

To evaluate the predictive value of the evocative test (E.T.) in the diagnosis of pancreatitis, the E.T. was performed in 35 healthy subjects (group I), 65 patients with a presumptive clinical of chronic pancreatitis (group II), and 52 patients with proved chronic pancreatitis (group III). In group I, false positive results were obtained in 11,4% of the patients, the increase in lipase above the upper limit of normal was relatively small. The patients of group II gave abnormal E.T.'s in 63%, reduced faecal chymotrypsin activities being found in 40%, and steatorrhea in 28% of the cases. Positive E.T.'s were associated with abnormal chymotrypsin and faecal fat determinations in 51% and 27%, respectively. In group III,, a positive E.T. was obtained in 60%, the test results show a signifikant negative correlation with the extent of pancreatic exocrine insufficiency. In group of patients with confirmed chronic pancreatitis but without steatorhea, the E.T. was positive in 72%. The E.T. has a limited value in the diagnosis of early stages of chronic pancreatitis.

摘要

为评估激发试验(E.T.)在胰腺炎诊断中的预测价值,对35名健康受试者(I组)、65名临床疑似慢性胰腺炎患者(II组)和52名已确诊慢性胰腺炎患者(III组)进行了激发试验。在I组中,11.4%的患者出现假阳性结果,脂肪酶升高超过正常上限的幅度相对较小。II组患者中63%的激发试验结果异常,40%的患者粪便糜蛋白酶活性降低,28%的患者出现脂肪泻。激发试验阳性分别与51%的患者糜蛋白酶异常和27%的患者粪便脂肪测定异常相关。在III组中,60%的患者激发试验呈阳性,试验结果与胰腺外分泌功能不全的程度呈显著负相关。在确诊为慢性胰腺炎但无脂肪泻的患者组中,72%的激发试验呈阳性。激发试验在慢性胰腺炎早期诊断中的价值有限。

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