Hellquist H, Lundgren J, Olofsson J
ORL J Otorhinolaryngol Relat Spec. 1984;46(3):153-8. doi: 10.1159/000275701.
5 cases of cholesterol granuloma are described, 3 within the maxillary sinuses and 2 within the frontal sinuses. The lesions arise from the mucosa and can be recognized on plain films and tomograms of the sinus as opacity, sometimes resembling a mucocele. Radical operation seems to give absolute cure without any recurrence. The pathogenesis is hemorrhage and/or filtration. The closed cavities of the paranasal sinuses provide favorable conditions for cholesterol to become dissociated from the lipoprotein complex and to precipitate and to give rise to a granulomatous reaction.
本文描述了5例胆固醇肉芽肿病例,其中3例位于上颌窦,2例位于额窦。病变起源于黏膜,在鼻窦平片和体层摄影上可表现为不透光区,有时类似黏液囊肿。根治性手术似乎能实现绝对治愈且无任何复发。其发病机制为出血和/或滤过。鼻窦的封闭腔隙为胆固醇从脂蛋白复合物中解离、沉淀并引发肉芽肿反应提供了有利条件。