Merz W A, Ballmer U
Pharmacopsychiatry. 1984 Mar;17(2):50-6. doi: 10.1055/s-2007-1017407.
Zung's Self-Rating Anxiety Scale (SAS) and Self-Rating Depression Scale (SDS) were completed by 489 healthy volunteers (314 men, 175 women) aged 15-84 years. The total scores were analysed in function of sex, age, occupational class, professional group, marital status, religion, foreigner status and nationality. Analysis by orthogonal polynomial regression showed no statistically significant differences between different age groups. In contrast to this, the study revealed highly significant SAS and SDS score differences between both sexes (Mann-Whitney U-test). In addition, there were statistically significant associations between the SAS scores and occupational class, professional group, religion, foreigner status and nationality; compared with significant associations between the SDS scores and marital status, foreigner status and nationality (Kruskal-Wallis test/Mann-Whitney U-test). The requirements for data analysis in clinical trials, for a differential diagnosis between transient variations of normal health and disorders, and for a differential diagnosis between anxiety and depression are discussed.
489名年龄在15至84岁之间的健康志愿者（314名男性，175名女性）完成了zung自评焦虑量表（SAS）和自评抑郁量表（SDS）。对总分按性别、年龄、职业阶层、专业组、婚姻状况、宗教、外国人身份和国籍进行分析。通过正交多项式回归分析表明，不同年龄组之间无统计学显著差异。与此相反，该研究揭示了两性之间SAS和SDS得分存在高度显著差异（曼-惠特尼U检验）。此外，SAS得分与职业阶层、专业组、宗教、外国人身份和国籍之间存在统计学显著关联；与SDS得分与婚姻状况、外国人身份和国籍之间的显著关联相比（克鲁斯卡尔-沃利斯检验/曼-惠特尼U检验）。讨论了临床试验中数据分析的要求、正常健康状态短暂变化与疾病之间的鉴别诊断以及焦虑和抑郁之间的鉴别诊断。
