Thickman D, Kundel H, Biery D
Radiology. 1984 Jul;152(1):113-6. doi: 10.1148/radiology.152.1.6729100.
The ability of magnetic resonance (MR) imaging to detect and distinguish various stages of obstruction in the canine kidney was investigated. MR images were obtained at acute, subacute, and chronic stages of experimentally produced hydronephrosis. The renal cortex was distinguished from the renal medulla in the normal dog and in the acute and subacute stages of hydronephrosis. T1 relaxation times of the renal cortex and medulla were measured in vitro in 14 normal and nine experimental animals. These values were used to compute the amount of tissue contrast between the cortex and medulla and were compared with the degree of corticomedullary differentiation seen in the image. A relationship was noted between increasing T1 values and increasing water content. Corticomedullary contrast decreased with obstruction. The variation in corticomedullary image contrast may be useful for assessing the duration of hydronephrosis.
研究了磁共振（MR）成像检测和区分犬肾梗阻不同阶段的能力。在实验性肾积水的急性、亚急性和慢性阶段获取了MR图像。在正常犬以及肾积水的急性和亚急性阶段，肾皮质与肾髓质得以区分。在14只正常动物和9只实验动物身上，体外测量了肾皮质和髓质的T1弛豫时间。这些值用于计算皮质和髓质之间的组织对比度，并与图像中所见的皮质髓质分化程度进行比较。观察到T1值增加与含水量增加之间存在关联。梗阻时皮质髓质对比度降低。皮质髓质图像对比度的变化可能有助于评估肾积水的持续时间。
