[Behavior of cultured cells on the surface of A12O3 ceramics of different consistencies].

The in vitro reactions of mesenchymal cell populations on different powdery and cubical Al2O3 ceramic implants are described compared with those on glass. The ceramics differ because of different compounds and surface processing. The physiologic eluate of the contaminated ceramics induce no cytotoxic and no antiproliverative effect on the single layer population in vitro. The cells settle itself on the ceramic surface. They constidued a confluent cell layer about the whole surface by proliferation (morphogenetic reaction). No difference in the behaviour of the fibroblast-like cells was observed referable to the chemical compound or the surface of the Al2O3 ceramics. The aluminium oxide ceramic presents itself as an absolutely bioinert material despite of strong soiling.