Kvinnsland S, Kvinnsland S
Acta Anat (Basel). 1984;119(2):94-8. doi: 10.1159/000145867.
Humoral factors play an important role in growth regulation. The growth regulatory activity in serum is a complex system with both growth-promoting and growth-inhibiting factors. In this study, using in vitro cartilage from rat nasal septum as target organ, evidence is presented that inhibiting activity does exist in normal rat serum. This activity seems to play a role in modulating cartilage growth rate in young, normal animals. Furthermore, a significant interaction between age in cartilage and age in serum as regards influence on cartilage growth was found.
体液因子在生长调节中起重要作用。血清中的生长调节活性是一个包含生长促进因子和生长抑制因子的复杂系统。在本研究中，以大鼠鼻中隔的体外软骨为靶器官，有证据表明正常大鼠血清中存在抑制活性。这种活性似乎在调节幼年正常动物的软骨生长速率中发挥作用。此外，还发现软骨年龄和血清年龄对软骨生长的影响之间存在显著相互作用。
