Copray J C
Department of Oral Biology, School of Dentistry, University of Groningen, The Netherlands.
J Anat. 1986 Feb;144:99-111.
The nasal septal cartilage from 4 days old rats was cultured in a serum-free chemically defined medium for 10 days to establish the intrinsic capacity for growth. Moreover, to obtain an indication of the separating potential, the maximal pressure generated by this growth was determined in a specially designed in vitro pressure registration system. The results show that, though to a lesser extent in comparison with the same period in vivo, the nasal septal cartilage increased considerably in size while the shape was preserved. The greatest force was generated by the longitudinally growing rod-like base of the nasal septal cartilage; the smallest force was generated by growth in height. The in vitro growth behaviour and growth pressure characteristics of the nasal septal cartilage corresponded with those previously found for epiphyseal cartilage. The present results suggest a prominent role for the nasal septal cartilage in midfacial outgrowth in the rat.
将4日龄大鼠的鼻中隔软骨在无血清化学限定培养基中培养10天，以确定其内在生长能力。此外，为了获得分离潜能的指标，在专门设计的体外压力记录系统中测定这种生长产生的最大压力。结果表明，与体内同期相比，鼻中隔软骨虽然生长程度较小，但尺寸显著增加，同时形状得以保留。鼻中隔软骨纵向生长的棒状基部产生的力最大；高度生长产生的力最小。鼻中隔软骨的体外生长行为和生长压力特征与先前在骺软骨中发现的特征一致。目前的结果表明鼻中隔软骨在大鼠面中部生长中起重要作用。
