抑郁症患者对睡眠剥夺和卡马西平反应的关系。

Relationship of response to sleep deprivation and carbamazepine in depressed patients.

作者信息

Roy-Byrne P, Uhde T W, Post R M, Joffe R T

出版信息

Acta Psychiatr Scand. 1984 May;69(5):379-82. doi: 10.1111/j.1600-0447.1984.tb02508.x.

DOI:10.1111/j.1600-0447.1984.tb02508.x

Abstract

The responses of 16 patients with major depressive disorder to one night's sleep deprivation and a subsequent double-blind, placebo-controlled trial of carbamazepine were compared. There was a significant association between the presence or absence of an antidepressant response to each of these treatments. Further studies are required to assess the clinical utility of this relationship and whether it is based on antidepressant response to any agent or is more specific to carbamazepine.

摘要

对16名重度抑郁症患者一晚睡眠剥夺后的反应以及随后进行的卡马西平双盲、安慰剂对照试验的反应进行了比较。这些治疗中每种治疗是否有抗抑郁反应之间存在显著关联。需要进一步研究来评估这种关系的临床实用性，以及它是基于对任何药物的抗抑郁反应还是更特定于卡马西平。