Youkey J R, Clagett G P, Rich N M, Brigham R A, Orecchia P M, Salander J M
Ann Surg. 1984 Jun;199(6):703-9. doi: 10.1097/00000658-198406000-00008.
Eighty-three femoral anastomotic false aneurysms occurring in 51 patients were diagnosed from 1972 through 1982. Twenty-two (27%) presented with acute events. Seventy (84%) were confirmed by sonography and/or arteriography. Bilaterality (29%), recurrence (18%), and associated aortic false aneurysms (8%) were significant problems. Eight-one were repaired with a six per cent complication rate, including one death related to preoperative rupture. The 51 patients were evaluated for associated illnesses, risk factors, and etiologies of their false aneurysms. The most common single cause (61%) was host vessel degeneration with an intact suture line remaining attached to a disrupted Dacron limb. Twenty-three patients with host vessel degeneration were matched with case controls not developing false aneurysms. These two groups were matched for gender, age, and year of AFB and compared for associated illnesses and risk factors. Incidences of cigarette smoking, hypertension, cerebrovascular disease, coronary artery disease, diabetes mellitus, previous femoral endarterectomy, outflow disease, other aneurysmal disease, multiple groin operations, wound complications, and training levels of surgeons performing initial AFBs were similar for both groups. Factors observed significantly more often in patients who developed false aneurysms included serum lipid abnormalities (p less than 0.05), braided synthetic suture material as opposed to monofilament polypropylene (p less than 0.05), and continued abuse of tobacco following AFB (p less than 0.005).
1972年至1982年间,对51例患者发生的83处股动脉吻合口假性动脉瘤进行了诊断。22例(27%)出现急性事件。70例(84%)经超声检查和/或动脉造影确诊。双侧病变(29%)、复发(18%)以及合并主动脉假性动脉瘤(8%)是严重问题。81处病变接受了修复,并发症发生率为6%,其中1例死亡与术前破裂有关。对51例患者的相关疾病、危险因素及假性动脉瘤的病因进行了评估。最常见的单一病因(61%)是宿主血管退变,完整的缝线附着于断裂的涤纶血管分支。23例发生宿主血管退变的患者与未发生假性动脉瘤的病例对照进行匹配。两组在性别、年龄和主动脉-股动脉搭桥术(AFB)年份方面进行匹配,并比较相关疾病和危险因素。两组患者在吸烟、高血压、脑血管疾病、冠状动脉疾病、糖尿病、既往股动脉内膜切除术、流出道疾病、其他动脉瘤性疾病、多次腹股沟手术、伤口并发症以及实施初次AFB的外科医生的培训水平等方面的发生率相似。在发生假性动脉瘤的患者中显著更常观察到的因素包括血脂异常(p<0.05)、使用编织合成缝线材料而非单丝聚丙烯缝线(p<0.05)以及AFB后持续吸烟(p<0.005)。