Bond C A, Monson R
Arch Intern Med. 1984 Jun;144(6):1159-62.
We analyzed the effectiveness of an intervention program involving a clinical pharmacist and nurse clinician in improving drug documentation in medical records, patient compliance, and disease control. Medical records and prescription files were reviewed for patients in a rheumatology and renal clinic. Compliance was estimated by examining prescription refill patterns. Reviews were performed before intervention (control group), nine months after intervention (study group 1), and four years nine months after our intervention program began (study group 2). A six-month retrospective analysis at each review point demonstrated a significant improvement in drug documentation, compliance, and disease control--BP--for both study groups. A significant correlation was found between compliance (refill patterns) and BP control--correlation coefficient phi for the control group, 67 for study group 1, and .89 for study group 2. Cost reductions associated with our intervention program suggest that this program is cost-effective.
我们分析了一项由临床药剂师和护士参与的干预项目在改善病历中的用药记录、患者依从性和疾病控制方面的有效性。对一家风湿病和肾脏科诊所的患者病历及处方档案进行了审查。通过检查处方续配模式来评估依从性。在干预前（对照组）、干预九个月后（研究组1）以及我们的干预项目开始四年零九个月后（研究组2）进行审查。在每个审查点进行的为期六个月的回顾性分析表明，两个研究组在用药记录、依从性和疾病控制（血压）方面均有显著改善。依从性（续配模式）与血压控制之间存在显著相关性——对照组的相关系数为0.67，研究组1为0.76，研究组2为0.89。与我们的干预项目相关的成本降低表明该项目具有成本效益。
