木糖氧化无色杆菌所致角膜溃疡
Corneal ulcer due to Achromobacter xylosoxidans.
作者信息
Newman P E, Hider P, Waring G O, Hill E O, Wilson L A, Harbin T S
出版信息
Br J Ophthalmol. 1984 Jul;68(7):472-4. doi: 10.1136/bjo.68.7.472.
Abstract
We report a case of corneal ulcer caused by the opportunistic organism Achromobacter xylosoxidans which developed during chronic topical steroid treatment of an eye with neovascular glaucoma. A. xylosoxidans has probably been underreported as a cause of ocular infection because of confusion between this organism and other Gram-negative organisms, particularly pseudomonas. A. xylosoxidans is resistant to aminoglycosides and some cephalosporins but not carbenicillin. This difference in antibiotic sensitivity patterns between A. xylosoxidans and pseudomonas makes an accurate differentiation between the 2 organisms important. This case was successfully treated after substituting topical carbenicillin for topical gentamicin and amikacin.
摘要
我们报告了1例由木糖氧化无色杆菌引起的角膜溃疡病例，该病例发生于对1例新生血管性青光眼患者进行长期局部类固醇治疗期间。由于木糖氧化无色杆菌与其他革兰氏阴性菌（特别是假单胞菌）之间存在混淆，其作为眼部感染病因的报道可能较少。木糖氧化无色杆菌对氨基糖苷类和某些头孢菌素耐药，但对羧苄青霉素不耐药。木糖氧化无色杆菌与假单胞菌在抗生素敏感性模式上的这种差异使得准确区分这两种细菌很重要。在用局部羧苄青霉素替代局部庆大霉素和阿米卡星后，该病例得到了成功治疗。
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